In this episode, I’ll discuss the Sepsis-Induced Coagulopathy (SIC) Score.
The Sepsis-Induced Coagulopathy (SIC) Score predicts likelihood of sepsis-induced coagulopathy.
This scoring system is specifically designed for predicting coagulation disturbances in sepsis using the Sepsis-3 definition.
The SIC score addresses 3 domains for a possible 0 to 6 points and was developed based on the results of logistic regression analyses identifying 3 independent predictors of a fatal outcome.
The 3 domains assessed are INR, platelet count, and total SOFA score.
An INR of <1.3, 1.3 to 1.4, and greater than 1.4 corresponds to a score of 0,1, or 2 points. A platelet count of at least 150,000, 100,000 to <150,000, and less than 100,000 corresponds to a score of 0,1, or 2 points. A total SOFA score of 0, 1, or 2 or more corresponds to a score of 0,1, or 2 points. For the SIC score to be diagnostic for sepsis-induced coagulopathy, the total score must be at least 4 AND the total score of the INR and platelet domains must be at least 3. Sepsis-induced coagulopathy is considered an earlier phase of disseminated intravascular coagulation, and this SIC scoring system can be used to help identify patients that are at higher risk for mortality and who might have or develop sepsis-induced disseminated intravascular coagulation.
To access my free download area with 20 different resources to help you in your practice, go to pharmacyjoe.com/free.
If you like this post, check out my book – A Pharmacist’s Guide to Inpatient Medical Emergencies: How to respond to code blue, rapid response calls, and other medical emergencies.